Protein-Protein Interaction, Protein Hub Confirmation of Organized Modularity in the Yeast Interactome Bertin N, Simonis N, Dupuy D, Cusick ME, Han JDJ, et al. PLoS Biology Vol. 5, No. 6, e153 ----------------------------------------------------------- Gene Name, Synonyms, SGD ID, Gene Ontology, Molecular Weight, GRAVY, pI Saccharomyces Genome Database ftp://ftp.yeastgenome.org/yeast/ downloaded 31/03/08 ----------------------------------------------------------- SwissProt Accession No, Protein Function, Description, Post-Translational Modifications Swiss-Prot The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 35:D193-D197(2007). http://au.expasy.org downloaded 15/05/08 ----------------------------------------------------------- Localization Huh, et al., Nature 425, 686-691 (2003) Protein Abundance Data Ghaemmaghami, et al., Nature 425, 737-741 (2003) http://yeastgfp.ucsf.edu/allOrfData.txt downloaded 15/05/08 ----------------------------------------------------------- Protein Complex Data A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality GT Hart, I Lee, EM Marcotte BMC Bioinformatics. 2007; 8: 236. Proteome survey reveals modularity of the yeast cell machinery. Gavin AC, et al. Nature. 2006 Mar 30;440(7084):631-6. ----------------------------------------------------------- Gene Expression Data Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization Spellman, P. T., Sherlock, G., Zhang, M. Q., Iyer, V. R., Anders, K., Eisen, M. B., Brown, P. O., Botstein, D. and Futcher, B. Mol Biol Cell. 1998; 9, 3273Ð3297. Genomic expression programs in the response of yeast cells to environmental changes Gasch, A. P., Spellman, P. T., Kao, C. M., Carmel-Harel, O., Eisen, M. B., Storz, G., Botstein, D. and Brown, P. O. Mol Biol Cell. 2000; 11, 4241Ð4257. ----------------------------------------------------------- Protein Abundance Data Picotti, P., Bodenmiller, B., Mueller, L. N., Domon, B. and Aebersold, R. (2009). Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell 138, 795Ð806.