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Services

We are funded to provide collaborative bioinformatics expertise and services to users of NCRIS-funded genomic and proteomic facilities.
For researchers in non-profit organizations in the state of New South Wales, these services are provided free of charge.

We have access to high performance computers, including the 256-processor cluster 'McLaren' at the AC3 data centre.

We can provide data analysis expertise in the following -omics areas:

Systems Biology & Integration

  • Contextualisation of data into ontological classes, biochemical and metabolic pathways and networks
  • Construction of genetic and protein-protein interaction networks
  • High dimensionality visualisation using custom and off the shelf tools
  • Interpretation of transcriptomic and proteomic data in a clinical context (epidemiological or individual patients)

Proteomics

  • LC-MS-MS experimental design
  • Data collation and summation from large LC-MS-MS experiments
  • Analysis of data from comparative studies using isotopic labels
  • Univariate and multivariate statistical analysis of protein expression data from LC-MS-MS analysis and 2-D gels
  • Interpretation and abstraction of protein identification data
  • Extraction and normalization of data from 2-D gels to assay inter-experiment reproducibility

Genomics & Transcriptomics

  • Microarray experimental design – essential to ensure the analysis of adequate sample numbers and replicates to generate valid data
  • Data extraction and normalization – to ensure inter-experiment reproducibility
  • Univariate and multivariate statistical analysis of gene expression data – to find genes or groups of genes that are similarly or differentially expressed
  • Genomic and EST sequence assembly, annotation and analysis
  • Data interpretation in genetic context, including the Human Haplotype
  • Data analysis, storage support and sequence analysis for new generation sequencing technology