Past projects – mammalian transcriptomics of differentiating osteoblasts, splice variation in Alzheimer’s
Natalie’s PhD focused on how the transcriptome changes during the differentiation of human mesenchymal stem cells into osteoblasts. This was a collaboration with Prof. Moustapha Kassem at the University of Southern Denmark. Natalie has also worked on many other mammalian transcriptomics projects, making an important and highly cited discovery of splice variation in the ApoE gene in Alzheimer’s disease. Natalie’s experience also includes non-mammalian transcriptomics research projects including assembly and analysis of the amphipod (Melita plumulosa), Sydney rock oyster (Saccostrea glomerata) and marine diatom (Ceratoneis closterium) transcriptomes.