The network basis of drug synergy

Collaborative work arising from the NHMRC project awarded to Carter, Wilkins, Chen.

Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response.
Pang CN, Lai YW, Campbell LT, Chen SC, Carter DA, Wilkins MR.
Sci Rep. 2017 Jan 12;7:40232. doi: 10.1038/srep40232.